Postnova Analytics – FFF Modules – PN3000 Detectors

The PN3000 Detectors from Postnova Analytics are designed to deliver unparalleled performance in Flow Field-Flow Fractionation (FFF) technology. These state-of-the-art detectors provide high sensitivity and precision, enabling accurate analysis and characterization of complex samples in various research and industrial applications.

Check out what models are available below!

AF2000 MF High Temperature Flow FFF Thermostat Module with integrated autosampler, channel and detector oven compartment and electronics unit, for advanced separation and characterization of polyolefin polymers, such as Polyethylene and Polypropylene. Temperature Range: Ambient to 220°C; Molar Mass Range: 10e3 to 10e12 Da; Particle Size Range 1 nm to 1000 nm. System comprising of one single integrated chassis inclunding moveable high temperature autosampler rack (25 sample vials, 5 mL volume) in lower system section, high temperature oven compartment for Flow FFF channels and detectors in the upper section, large top door for easy opening and access to channel and detectors as well as control electronics in the back part of the instrument and special Thermostat Control software connected to and running automated with NovaFFF. System can be equipped with various online high temperature detectors, which have to selected optional, such as High Temperature Infrared (HT-IR), Refractive Index (HT-RI), Multi-Angle Static Light Scattering (HT-MALS) and Viscometry (HT-VISCO). Additional Required Components: 1) High Temperature Flow FFF channel cartridge; 2) High Temp IR and/or additional detectors; 3) Control PC for NovaFFF and Thermostat Control software.

The PN5300 automatic sample injector includes the latest state-of-the-art auto injector technology, such as a double needle with positive headspace pressure, extensive wash routines for minimal carry over and three injection modes including micro liter pick-up mode for zero sample loss, huge injection range and full biocompatibility. Offering space for two deep well, shallow well or vial rack adapter plates, the PN5300 is ideally suited to be integrated with a wide range of different FFF systems. The newly designed Peltier cooling/heating keeps samples stable in a closed environment for maximum reproducibility. The temperature range from 4°C up to 40°C prevents degradation, evaporation or precipitation of sample during storage and processing with any FFF system.

With the introduction of the SF2000 G Postnova has launched a new type of Gravitational Splitt FFF. The SF2000 G is a the first true completely integrated and modular commercial G-Splitt including online optical particle detection. The machine can be used to separate, fractionate, purify and to characterize microparticles in one step. The attached PN3000 XPT detector allows determination of size and shape of the particle fractions eluting from the channel.

The system features a broad separation range from 1 to 300 µm depending on sample nature and has the ability to separate different shaped particle fractions from each other. The SF2000 G is clearly setting a new standard in the area of microparticle fractionation and marks a real break-through in Splitt science.

The system is using Postnovas unique G-Splitt FFF channel which can be re-used and cleaned after operation. Special pumps deliver and control all necessary in- and outlet flows and the attached PN3000 XPT detector provides further information about the particle fractions via its powerful software.

The 6MBA is the basic model offered within the Ray-Ran Range of Melt Flow Indexers. The manually operated test procedure is very simple to undertake. Molten Polymer is extruded through a closely controlled orifice (die) from the apparatus using pre set conditions of temperature and pressure produced by a dead weight system. The extruded polymer is cut off manually and is then weighed. Using the time interval to extrude the polymer its flow rate over 10 minutes can easily be determined, thus giving the Melt Flow Index (MFI) or Melt Mass Flow Rate (MFR) in g/10 min. By conducting a simple Density Test at test temperature on the same material using the same pre set conditions and a known piston travel distance the Melt Volume Rate (MVR) can also be determined.

The 6MPCA is the most advanced model offered within the Ray-Ran Range of Melt Flow Indexers. The operating procedure is very simple to undertake using its on board advanced microprocessor technology. The large liquid crystal display (LCD) provides simple on screen instructions reducing user error and the test parameters are easily entered via the alpha numeric membrane keypad. The apparatus can accurately determine results for MFR, MVR and Density at test temperature.

Bulk density apparatus is testing equipment used to measure the bulk density property of powder, granules and other “divided” solids, especially used in reference to mineral components (soil, gravel, sand), chemical substances, (pharmaceutical), plastics like polyethylene (hdpe or mdpe) pvc, polystyrene etc, or foodstuff and any other masses of granular or particulate matter.

The Method A tester is primarily used to measure the apparent density of fine granules that can be poured readily through a “V” shaped funnel, the material under test is allowed to flow into a cylindrical cup with a known volume of 100cm³.

The Auto Density Gradient Apparatus from Ray-Ran has become the world’s benchmark for accurate density measurement of small solid specimens using the column method. Offered as a 3 or 6 column version, the built-in on-board Microprocessor System accurately calculates the specimen’s density more quickly and more accurately by using the latest linear encoder technology that measures the samples position in the column relative to the calibrated glass marker floats. Once the correct position of the sample is recorded the density is displayed on the LCD screen.

MagCore® HF48 is a powerful system with consistent and simultaneous processing of 1st~24th or 24th~48th samples of DNA/RNA at A/B operation zones. It provides fast, cost-effective, and automated extraction purification of nucleic acids from diverse sample types including whole blood, bacteria cells, plant cells, cultured cells, virus particles and tissues. With a sterilization system built-in, optimized protocols pre-programmed and magnetic bead-based reagent cartridges supplied, MagCore® HF48 provides users a fast, efficient and cross-contamination-free isolation of various DNA/RNA samples. Its superb processing capacity makes itself a perfect solution for high-capacity nucleic acid purification.

MagCore® Super is RBC Bioscience’s most advanced and efficient robotic workstation for nucleic acid extraction. It is the first platform combining EXTRACTOR and SPECTROPHOTOMETER. Users are benefited with automatic purification, OD values retrieval and final eluate concentration measurement. It is equipped with a colored touch screen, thermo printer, barcode scanner, USB flash p&p.

Innovation at Your Fingertips

RedShiftBio’s AQS³pro overcomes many of the limitations of traditional spectroscopy-based technologies with ultrasensitive, highly reproducible, automated structural measurements of proteins and other biomolecules. It can be used for a wide range of applications from formulation development of mAb-based biotherapeutics to robust measurements of ADCs, AAVs, and mRNA. Powered by Microfluidic Modulation Spectroscopy (MMS), the AQS³pro is designed to provide five key measurements— aggregation, quantitation, stability, similarity, structure—directly supports biomolecule characterization throughout the biopharmaceutical development pipeline.

Key features:

• Ability to measure wide range of native sample concentrations from 200 mg/ml
• Fully automated sample-handling, with both 24 and 96 well plate formats
• Real-time background subtraction eliminates need to dialyze samples
• Detection of <2% change in secondary structure even at low concentrations
• Advanced onboard data analytics enabling rapid and robust data interpretation and reporting